17th Annual ECSS-Congress, Bruges 2012

Abstract details

Abstract-ID: 1221
Session: [MO-PM35] Nutrition & Body Composition
Lecture room: G103
Date & time: 03.07.2014 / 15:00 - 16:00
Title of the paper: EFFECTS OF SPONTANEOUS PHYSICAL ACTIVITY AND FOOD CALORIE ON COGNITIVE FUNCTIONS OF THE RAT
Authors: Felszeghy, K.1, Pósa, A.2, Varga, D.2, Varga, C.2, Nyakas, C.1, Radák, Z.1
Institution: 1: Semmelweis University ; 2: University of Szeged
Department: 1:Research Laboratory of Sport Sci 2: Department of Physiology, Morphology and Neurobiology
Country: Hungary
Abstract text Introduction It has been well established that both physical activity and calorie restriction elicit improving effect on learning and memory functions. On the other hand, high triglyceride content of the diet, as well as, inactive living style has several adverse physiological effects and negatively influences cognition. In the recent study rats were used to examine the impact of regular voluntary physical exercise on the cognitive performance of the animals. Moreover, the effect of the diet calorie content on the learning capacity was estimated by a well evaluated spatial learning task, the Morris water maze. Methods Adult male Wistar rats were separated into inactive and running groups. Inactive animals were placed by three into normal cages, while running animals were placed separately into cages containing running wheel that can be used voluntary. Both groups were distributed further into three diet groups as follows: standard food consumed ad libitum as “control group”; calorie restriction consumed 25g standard food per animal as “calorie restriction group”, high triglyceride containing diet consumed 60% standard food and 40% grease as “high triglyceride group”. Following 12 weeks of treatments animals were tested in Morris water maze for spatial learning ability. Results A significant interaction was found between diet and physical activity concerning their effect on learning performance. Spontaneous running activity improved working memory (short-term memory) but weakened reference memory (long-term memory) of the control rats receiving standard food. Physical activity impaired the performance in calorie-restricted group. A considerable enhancement of working memory occurred following calorie restriction in inactive animals. Regular running activity improved working memory in animals received high triglyceride containing food leaving unaltered the reference memory function. Discussion Our results indicate that in inactive animals calorie restriction can enhance cognitive capacity, but induces impairment if a regular physical activity is present. High calorie intake strongly weakens cognitive performance in inactive animals, but results in less impairment together with regular running. Moreover, we can conclude that short-term memory is more sensitive to the alteration either in physical activity state or in diet than long-term memory. Contact kfelsz2008@gmail.com
Topic: Nutrition
Keyword I: spontaneous physical activity
Keyword II: calorie restriction
Keyword III: cognitive functions